When administered into the drug is well absorbed and reaches high concentrations in the blood. Fuzidin- sodium penetrates into the skin, subcutaneous tissue, lungs, liver tissue, bone, pleural fluid, cartilage and connective tissues, crosses the placental barrier clomid and is excreted in breast milk. It derived from the body mainly in the bile and, to a lesser extent, by the kidneys.
Septicemia, pneumonia, otitis media, lung abscess, cellulitis, furunculosis, infected burns and wounds, soft tissue infections, osteomyelitis, gonorrhea caused by strains resistant to benzylpenicillin gonorrhea, increased patient sensitivity to penicillin.
Hypersensitivity to the drug, giperprotrombinemiya, children up to 3 years.
Chronic renal failure.
Pregnancy and lactation
fuzidin- sodium clomid displace bilirubin from binding with plasma proteins, thereby increasing the risk of kernicterus. Therefore, if you must use during pregnancy should be evaluated anticipated benefit to the mother and the potential risk to the fetus.
Dosage and administration
. Inside after eating adults: a single dose is usually 0.5 grams daily – 1,5 g (in 3 divided doses every 8 hours). In severe infections administered in the first 2 days to 2 – 3 g per day, then reduce the dose (up to 1.5 g per day). The average duration of treatment – 7 – 14 days, osteomyelitis – 2 – 3 weeks or more. Children: from 3 to 4 years – 40 – 60 mg / kg / day, 4 years and older – 20 – 40 mg / kg / day , the daily dose divided into 3 admission. The duration of the treatment – 7 – 10 days, in the treatment of osteomyelitis – 2 – 3 weeks or more.
Abdominal pain, nausea, regurgitation, vomiting, diarrhea, allergic phenomena (redness of the mucous membranes of the mouth and throat, pain when swallowing and skin rash), eosinophilia.
Interactions with other drugs
Interactions has been insufficiently studied and the data are ambiguous. Antacids delay absorption. Cholestyramine reduces plasma concentration.
Reduces (mutually) or does clomid not change the effect of rifampicin, some beta-lactam against a number of strains.
Glycopeptides, fluoroquinolones lower (relative) effect.
With benzylpenicillin gives a synergistic effect against penitsillinazoobrazuyuschih staphylococci and additive – against susceptible to benzylpenicillin. The combined use of macrolides as pronounced synergistic effect is observed; tetracycline, chloramphenicol and streptomycin often additive effect.
In severe the disease and the need for long-term treatment is recommended combination of sodium with semi-synthetic penicillins and tetracyclines, which improves efficiency and prevents the emergence of resistant organisms. Dyspepsia caused by local irritant effect of the drug on the mucosa of the gastrointestinal tract. To prevent and reduce drug taking liquid food.
With the development of allergic phenomena drug overturned and conduct desensitizing therapy.
Antibiotic reserve for infections caused by strains resistant to penicillin and other antibiotics.
Tablets, enteric-coated tablets, 125 mg and 250 mg. On 20 tablets in banks orange glass or plastic jars.
10 tablets in blisters film clomid and aluminum foil or paper printed patent coated. One jar or 2 blisters with instruction on use are placed in a pile of cardboard.
2 years. Do not use beyond the expiration date printed on the package